Back in 1999, while working for IBM Canada, I've made a friend who had access to all kinds of software and he introduced me to Maya which is one of the better known 3D suites (now) made by Autodesk.
Eventually I tried all available programs such as 3dsMax, SideFX Houdini (which I still like very much) and Blender.
Blender made the most sense to me so I've invested a lot of time to learn how to model, texture and render animations. Eventually I've discovered Cinema4D which was an even better match for my work flow and for a while, provided corporate training for this software application.
Last year, when I created virtual instruments for creative children, I've used a CAD application and then imported the mesh into Cheetah3D for texturing and the finall renders as seen in the images above and bellow.
Once I'm happy with the rendered images, I bring them into Flash where I can attach various events and functions via ActionScript and once that is done, I upload the SWF files to my server. The results of that process can be seen at the LittleComposers.org homepage.

I had a lot of fun designing the UI for the "Little Composers Piano" which is available in iTunes for the Apple iPad.
If I have some free time, I'll post new renders of new artwork currently in production.